Thymol Crystals

Thymol Crystals (2-Isopropyl-5-methylphenol)

Synonyms: Thymol, Thyme Camphor | Natural Source: Thymus vulgaris / Ajwain Oil [cite: 203]

CAS: 89-83-8 FEMA: 3066 Formula: C₁₀H₁₄O Assay ≥ 99.0%

Grade: Pharma / Food / Flavour / Cosmetic[cite: 203].

Organoleptic Specification

AppearanceWhite crystalline powder/crystals [cite: 205]
OdourStrong, warm, thyme-like [cite: 205]
TastePungent, slightly sweet [cite: 205]
SolubilitySoluble in alcohol, oils [cite: 205]

Purity & Safety

Heavy Metals≤ 10 ppm
Arsenic≤ 3 ppm
Lead≤ 5 ppm
Residual SolventsAs per ICH limits

Physico-Chemical Data

Assay (GC/HPLC)≥ 99.0 %
Melting Point48 – 51 °C
Specific Gravity @ 25 °C0.960 – 0.980
Refractive Index @ 20 °C1.520 – 1.525 (molten)
Acid Value≤ 1.0 mg KOH/g
Loss on Drying≤ 0.5 %

Typical Certificate of Analysis (COA)

Test Parameter Specification Typical Result
Assay (GC/HPLC)≥ 99.0 % [cite: 213]99.5 % [cite: 213]
Melting Point48 – 51 °C [cite: 213]49.6 °C [cite: 213]
Loss on Drying≤ 0.5 % [cite: 213]0.2 % [cite: 213]
Heavy Metals≤ 10 ppm [cite: 213]Conforms [cite: 213]

Conclusion: The tested batch conforms to specification and is suitable for pharma, food, and flavour use[cite: 214].